Don’t inhibit yeast growth
Kill it with BREXAFEMME1
Don’t inhibit yeast growth
Kill it with BREXAFEMME1
Don’t inhibit yeast growth
Kill it with BREXAFEMME1
A broad-spectrum* triterpenoid antifungal with fungicidal activity1
BREXAFEMME belongs to a novel class known as triterpenoid antifungals1
BREXAFEMME works by blocking glucan synthase, an enzyme present in fungal cells but not human cells1
This disrupts the fungal cell wall integrity, leading to cell death. This fungicidal activity kills Candida1*
BREXAFEMME belongs to a novel class known as triterpenoid antifungals1
BREXAFEMME works by blocking glucan synthase, an enzyme present in fungal cells but not human cells1
This disrupts the fungal cell wall integrity, leading to cell death. This fungicidal activity kills Candida1*
BREXAFEMME has broad-spectrum activity1*
Clinical efficacy shown vs Candida species, including albicans | ![]() |
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In vitro activity vs non-albicans Candida | ![]() |
In vitro activity vs fluconazole-resistant strains | ![]() |
Vaginal tissue penetration† | ![]() |
Retains activity in low pH‡ | ![]() |
*Based on in vitro studies. Clinical significance is unknown.1
†In animal studies, BREXAFEMME exhibited vaginal tissue penetration after oral administration—reaching up to 9 times the plasma concentration.1
‡BREXAFEMME retained antifungal activity based on minimal inhibitory concentration values when tested at pH 4.5 (the normal vaginal pH).1